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Number of T Reg Cells That Differentiate Does Not Increase upon Encounter of Agonist Ligand on Thymic Epithelial Cells

It has been reported that the differentiation of CD4(+)CD25(+) regulatory T cells (T reg cells) can be induced by agonist peptide/major histocompatibility complex ligands in the thymus. Exploiting a transgenic mouse line wherein expression of a particular T cell epitope can be controlled temporally...

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Detalles Bibliográficos
Autores principales: van Santen, Hisse-Martien, Benoist, Christophe, Mathis, Diane
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211925/
https://www.ncbi.nlm.nih.gov/pubmed/15534371
http://dx.doi.org/10.1084/jem.20041022