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Number of T Reg Cells That Differentiate Does Not Increase upon Encounter of Agonist Ligand on Thymic Epithelial Cells
It has been reported that the differentiation of CD4(+)CD25(+) regulatory T cells (T reg cells) can be induced by agonist peptide/major histocompatibility complex ligands in the thymus. Exploiting a transgenic mouse line wherein expression of a particular T cell epitope can be controlled temporally...
Autores principales: | van Santen, Hisse-Martien, Benoist, Christophe, Mathis, Diane |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211925/ https://www.ncbi.nlm.nih.gov/pubmed/15534371 http://dx.doi.org/10.1084/jem.20041022 |
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