Cargando…

Maintenance of T Cell Specification and Differentiation Requires Recurrent Notch Receptor–Ligand Interactions

Notch signaling has been shown to play a pivotal role in inducing T lineage commitment. However, T cell progenitors are known to retain other lineage potential long after the first point at which Notch signaling is required. Thus, additional requirements for Notch signals and the timing of these eve...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmitt, Thomas M., Ciofani, Maria, Petrie, Howard T., Zúñiga-Pflücker, Juan Carlos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211933/
https://www.ncbi.nlm.nih.gov/pubmed/15314075
http://dx.doi.org/10.1084/jem.20040394