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Maintenance of T Cell Specification and Differentiation Requires Recurrent Notch Receptor–Ligand Interactions
Notch signaling has been shown to play a pivotal role in inducing T lineage commitment. However, T cell progenitors are known to retain other lineage potential long after the first point at which Notch signaling is required. Thus, additional requirements for Notch signals and the timing of these eve...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211933/ https://www.ncbi.nlm.nih.gov/pubmed/15314075 http://dx.doi.org/10.1084/jem.20040394 |