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Primary HIV-1 Infection Is Associated with Preferential Depletion of CD4(+) T Lymphocytes from Effector Sites in the Gastrointestinal Tract

Given its population of CCR5-expressing, immunologically activated CD4(+) T cells, the gastrointestinal (GI) mucosa is uniquely susceptible to human immunodeficiency virus (HIV)-1 infection. We undertook this study to assess whether a preferential depletion of mucosal CD4(+) T cells would be observe...

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Detalles Bibliográficos
Autores principales: Mehandru, Saurabh, Poles, Michael A., Tenner-Racz, Klara, Horowitz, Amir, Hurley, Arlene, Hogan, Christine, Boden, Daniel, Racz, Paul, Markowitz, Martin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211967/
https://www.ncbi.nlm.nih.gov/pubmed/15365095
http://dx.doi.org/10.1084/jem.20041196