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Primary HIV-1 Infection Is Associated with Preferential Depletion of CD4(+) T Lymphocytes from Effector Sites in the Gastrointestinal Tract
Given its population of CCR5-expressing, immunologically activated CD4(+) T cells, the gastrointestinal (GI) mucosa is uniquely susceptible to human immunodeficiency virus (HIV)-1 infection. We undertook this study to assess whether a preferential depletion of mucosal CD4(+) T cells would be observe...
Autores principales: | Mehandru, Saurabh, Poles, Michael A., Tenner-Racz, Klara, Horowitz, Amir, Hurley, Arlene, Hogan, Christine, Boden, Daniel, Racz, Paul, Markowitz, Martin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211967/ https://www.ncbi.nlm.nih.gov/pubmed/15365095 http://dx.doi.org/10.1084/jem.20041196 |
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