Tumor Necrosis Factor (TNF) Receptor Shedding Controls Thresholds of Innate Immune Activation That Balance Opposing TNF Functions in Infectious and Inflammatory Diseases

Tumor necrosis factor (TNF) is a potent cytokine exerting critical functions in the activation and regulation of immune and inflammatory responses. Due to its pleiotropic activities, the amplitude and duration of TNF function must be tightly regulated. One of the mechanisms that may have evolved to...

Descripción completa

Detalles Bibliográficos
Autores principales: Xanthoulea, Sofia, Pasparakis, Manolis, Kousteni, Stavroula, Brakebusch, Cord, Wallach, David, Bauer, Jan, Lassmann, Hans, Kollias, George
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211976/
https://www.ncbi.nlm.nih.gov/pubmed/15289505
http://dx.doi.org/10.1084/jem.20040435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211976/
https://www.ncbi.nlm.nih.gov/pubmed/15289505
http://dx.doi.org/10.1084/jem.20040435

Ejemplares similares