Anthrolysin O and Other Gram-positive Cytolysins Are Toll-like Receptor 4 Agonists

Exposure of bone marrow–derived macrophages (BMDMs) to low concentrations of Bacillus anthracis lethal toxin (LT), whose catalytic subunit is lethal factor (LF), results in induction of a robust apoptotic response dependent on activation of Toll-like receptor (TLR)4. A similar TLR4-dependent apoptot...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Jin Mo, Ng, Vincent H., Maeda, Shin, Rest, Richard F., Karin, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211988/
https://www.ncbi.nlm.nih.gov/pubmed/15611291
http://dx.doi.org/10.1084/jem.20041215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211988/
https://www.ncbi.nlm.nih.gov/pubmed/15611291
http://dx.doi.org/10.1084/jem.20041215

Ejemplares similares