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Mycobacterium tuberculosis pks12 Produces a Novel Polyketide Presented by CD1c to T Cells
CD1c-mediated T cells are activated by a mycobacterial phospholipid antigen whose carbohydrate structure precisely corresponds to mammalian mannosyl β-1-phosphodolichol (MPD), but contains an unusual lipid moiety. Here, we show that this T cell antigen is a member of a family of branched, alkane lip...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211992/ https://www.ncbi.nlm.nih.gov/pubmed/15611286 http://dx.doi.org/10.1084/jem.20041429 |