Role of Dok-1 and Dok-2 in Leukemia Suppression
Chronic myelogenous leukemia (CML) is characterized by the presence of the chimeric p210(bcr/abl) oncoprotein that shows elevated and constitutive protein tyrosine kinase activity relative to the normal c-abl tyrosine kinase. Although several p210(bcr/abl) substrates have been identified, their rele...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211998/ https://www.ncbi.nlm.nih.gov/pubmed/15611295 http://dx.doi.org/10.1084/jem.20041306 |