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Role of Dok-1 and Dok-2 in Leukemia Suppression

Chronic myelogenous leukemia (CML) is characterized by the presence of the chimeric p210(bcr/abl) oncoprotein that shows elevated and constitutive protein tyrosine kinase activity relative to the normal c-abl tyrosine kinase. Although several p210(bcr/abl) substrates have been identified, their rele...

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Detalles Bibliográficos
Autores principales:	Niki, Masaru, Di Cristofano, Antonio, Zhao, Mingming, Honda, Hiroaki, Hirai, Hisamaru, Van Aelst, Linda, Cordon-Cardo, Carlos, Pandolfi, Pier Paolo
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211998/ https://www.ncbi.nlm.nih.gov/pubmed/15611295 http://dx.doi.org/10.1084/jem.20041306

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