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CD8 Epitope Escape and Reversion in Acute HCV Infection
In the setting of acute hepatitis C virus (HCV) infection, robust HCV-specific CD8(+) cytotoxic T lymphocyte (CTL) responses are associated with initial control of viremia. Despite these responses, 70–80% of individuals develop persistent infection. Although viral escape from CD8 responses has been...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212005/ https://www.ncbi.nlm.nih.gov/pubmed/15611288 http://dx.doi.org/10.1084/jem.20041006 |