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CD8 Epitope Escape and Reversion in Acute HCV Infection

In the setting of acute hepatitis C virus (HCV) infection, robust HCV-specific CD8(+) cytotoxic T lymphocyte (CTL) responses are associated with initial control of viremia. Despite these responses, 70–80% of individuals develop persistent infection. Although viral escape from CD8 responses has been...

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Detalles Bibliográficos
Autores principales: Timm, Joerg, Lauer, Georg M., Kavanagh, Daniel G., Sheridan, Isabelle, Kim, Arthur Y., Lucas, Michaela, Pillay, Thillagavathie, Ouchi, Kei, Reyor, Laura L., zur Wiesch, Julian Schulze, Gandhi, Rajesh T., Chung, Raymond T., Bhardwaj, Nina, Klenerman, Paul, Walker, Bruce D., Allen, Todd M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212005/
https://www.ncbi.nlm.nih.gov/pubmed/15611288
http://dx.doi.org/10.1084/jem.20041006