Cargando…

CD8 Epitope Escape and Reversion in Acute HCV Infection

In the setting of acute hepatitis C virus (HCV) infection, robust HCV-specific CD8(+) cytotoxic T lymphocyte (CTL) responses are associated with initial control of viremia. Despite these responses, 70–80% of individuals develop persistent infection. Although viral escape from CD8 responses has been...

Descripción completa

Detalles Bibliográficos
Autores principales:	Timm, Joerg, Lauer, Georg M., Kavanagh, Daniel G., Sheridan, Isabelle, Kim, Arthur Y., Lucas, Michaela, Pillay, Thillagavathie, Ouchi, Kei, Reyor, Laura L., zur Wiesch, Julian Schulze, Gandhi, Rajesh T., Chung, Raymond T., Bhardwaj, Nina, Klenerman, Paul, Walker, Bruce D., Allen, Todd M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212005/ https://www.ncbi.nlm.nih.gov/pubmed/15611288 http://dx.doi.org/10.1084/jem.20041006

Ejemplares similares

Mutational escape of CD8+ T cell epitopes: implications for prevention and therapy of persistent hepatitis virus infections
por: Timm, Joerg, et al.
Publicado: (2014)

Human hepatitis D virus-specific T cell epitopes
por: Kohsar, Matin, et al.
Publicado: (2021)

Increased CD56(bright) NK cells in HIV-HCV co-infection and HCV mono-infection are associated with distinctive alterations of their phenotype
por: Bhardwaj, Suvercha, et al.
Publicado: (2016)

Comprehensive Review of Human Plasmodium falciparum-Specific CD8+ T Cell Epitopes
por: Heide, Janna, et al.
Publicado: (2019)

Impaired Hepatitis C Virus-Specific T Cell Responses and Recurrent Hepatitis C Virus in HIV Coinfection
por: Kim, Arthur Y, et al.
Publicado: (2006)

German cohort of HCV mono-infected and HCV/HIV co-infected patients reveals relative under-treatment of co-infected patients
por: Beisel, Claudia, et al.
Publicado: (2014)

Broadly directed virus-specific CD4(+) T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence
por: Schulze zur Wiesch, Julian, et al.
Publicado: (2012)

Mucosal‐associated invariant T‐cell frequency and function in blood and liver of HCV mono‐ and HCV/HIV co‐infected patients with advanced fibrosis
por: Beudeker, Boris J. B., et al.
Publicado: (2017)

HCV-specific CD4+ T cells of patients with acute and chronic HCV infection display high expression of TIGIT and other co-inhibitory molecules
por: Ackermann, Christin, et al.
Publicado: (2019)

Treatment and re-treatment results of HCV patients in the DAA era
por: Piecha, Felix, et al.
Publicado: (2020)

T Lymphocytes, Multi-Omic Interactions and Bronchopulmonary Dysplasia
por: Toldi, Gergely, et al.
Publicado: (2021)

Transcriptional Pattern Analysis of Virus-Specific CD8+ T Cells in Hepatitis C Infection: Increased Expression of TOX and Eomesodermin During and After Persistent Antigen Recognition
por: Wildner, Nils H., et al.
Publicado: (2022)

The broad assessment of HCV genotypes 1 and 3 antigenic targets reveals limited cross-reactivity with implications for vaccine design
por: von Delft, Annette, et al.
Publicado: (2016)

Human Monoclonal Antibodies to a Novel Cluster of Conformational Epitopes on HCV E2 with Resistance to Neutralization Escape in a Genotype 2a Isolate
por: Keck, Zhen-yong, et al.
Publicado: (2012)

Detection of EXP1-Specific CD4+ T Cell Responses Directed Against a Broad Range of Epitopes Including Two Promiscuous MHC Class II Binders During Acute Plasmodium falciparum Malaria
por: Heide, Janna, et al.
Publicado: (2020)

The impact of level of neonatal care provision on outcomes for preterm babies born between 27 and 31 weeks of gestation, or with a birth weight between 1000 and 1500 g: a review of the literature
por: Ismail, Abdul Qader Tahir, et al.
Publicado: (2020)

Escape of Hepatitis C Virus from Epitope I Neutralization Increases Sensitivity of Other Neutralization Epitopes
por: Gu, Jun, et al.
Publicado: (2018)

Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA
por: Leslie, Alasdair, et al.
Publicado: (2005)

Ever closer to a prophylactic vaccine for HCV
por: Swadling, Leo, et al.
Publicado: (2013)

CTL Escape Mediated by Proteasomal Destruction of an HIV-1 Cryptic Epitope
por: Cardinaud, Sylvain, et al.
Publicado: (2011)

An Elite Controller of Picornavirus Infection Targets an Epitope That Is Resistant to Immune Escape
por: Bell, Michael P., et al.
Publicado: (2014)

Nutrition and Immunity in Perinatal Hypoxic-Ischemic Injury
por: Gandecha, Hema, et al.
Publicado: (2022)

Managerial thinking in neonatal care: a qualitative study of place of care decision-making for preterm babies born at 27–31 weeks gestation in England
por: Cupit, Caroline, et al.
Publicado: (2022)

Differential escape of HCV from CD8(+) T cell selection pressure between China and Germany depends on the presenting HLA class I molecule
por: Xia, Youchen, et al.
Publicado: (2018)

Limited T Cell Receptor Diversity of HCV-specific T Cell Responses Is Associated with CTL Escape
por: Meyer-Olson, Dirk, et al.
Publicado: (2004)

Structural Basis of HCV Neutralization by Human Monoclonal Antibodies Resistant to Viral Neutralization Escape
por: Krey, Thomas, et al.
Publicado: (2013)

Sofosbuvir plus velpatasvir for 8 weeks in patients with acute hepatitis C: The HepNet acute HCV-V study
por: Maasoumy, Benjamin, et al.
Publicado: (2022)

HCV–HIV Coinfection: Simple Messages from a Complex Disease
por: Klenerman, Paul, et al.
Publicado: (2007)

Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8(+) T Cells and Evolve at the Population Level
por: Karimzadeh, Hadi, et al.
Publicado: (2019)

Exploring variation in quality of care and clinical outcomes between neonatal units: a novel use for the UK National Neonatal Audit Programme (NNAP)
por: Ismail, Abdul-Qader Tahir, et al.
Publicado: (2022)

Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes
por: Palmer, Duncan, et al.
Publicado: (2013)

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope
por: Textor, Ana, et al.
Publicado: (2016)

Alterations in function and distribution of regulatory T Cells (Tregs) may blunt vaccine induced immune responses in HIV infection
por: van Lunzen, J, et al.
Publicado: (2012)

Immune escape pathways from the HBV core(18-27) CD8 T cell response are driven by individual HLA class I alleles
por: Walker, Andreas, et al.
Publicado: (2022)

Hurdles to the Development of Effective HBV Immunotherapies and HCV Vaccines
por: Torres-Cornejo, Almudena, et al.
Publicado: (2017)

Methodologies for the Analysis of HCV-Specific CD4(+) T Cells
por: Lokhande, Megha U., et al.
Publicado: (2015)

Mutational escape from CD8(+) T cell immunity: HCV evolution, from chimpanzees to man
por: Bowen, David G., et al.
Publicado: (2005)

Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design
por: Cowton, Vanessa M., et al.
Publicado: (2021)

Correction: Preventing tumor escape by targeting a post-proteasomal trimming independent epitope
por: Textor, Ana, et al.
Publicado: (2017)

Within-Epitope Interactions Can Bias CTL Escape Estimation in Early HIV Infection
por: Garcia, Victor, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_q1kehp90gihqeeqj2q0n3f4m5c