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Clinically Approved Heterocyclics Act on a Mitochondrial Target and Reduce Stroke-induced Pathology

Substantial evidence indicates that mitochondria are a major checkpoint in several pathways leading to neuronal cell death, but discerning critical propagation stages from downstream consequences has been difficult. The mitochondrial permeability transition (mPT) may be critical in stroke-related in...

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Detalles Bibliográficos
Autores principales: Stavrovskaya, Irina G., Narayanan, Malini V., Zhang, Wenhua, Krasnikov, Boris F., Heemskerk, Jill, Young, S. Stanley, Blass, John P., Brown, Abraham M., Beal, M. Flint, Friedlander, Robert M., Kristal, Bruce S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212009/
https://www.ncbi.nlm.nih.gov/pubmed/15263028
http://dx.doi.org/10.1084/jem.20032053