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Human Autoantibody Silencing by Immunoglobulin Light Chains

Several newly arising human antibodies are polyreactive, but in normal individuals the majority of these potentially autodestructive antibodies are removed from the repertoire by receptor editing or B cell deletion in the bone marrow. To determine what proportion of naturally arising autoantibodies...

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Detalles Bibliográficos
Autores principales: Wardemann, Hedda, Hammersen, Johanna, Nussenzweig, Michel C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212019/
https://www.ncbi.nlm.nih.gov/pubmed/15263026
http://dx.doi.org/10.1084/jem.20040818