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Human Autoantibody Silencing by Immunoglobulin Light Chains
Several newly arising human antibodies are polyreactive, but in normal individuals the majority of these potentially autodestructive antibodies are removed from the repertoire by receptor editing or B cell deletion in the bone marrow. To determine what proportion of naturally arising autoantibodies...
Autores principales: | Wardemann, Hedda, Hammersen, Johanna, Nussenzweig, Michel C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212019/ https://www.ncbi.nlm.nih.gov/pubmed/15263026 http://dx.doi.org/10.1084/jem.20040818 |
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