C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation

After cell death, via apoptosis or necrosis, the uptake of dead cells by neighboring cells or phagocytes prevents the release of intracellular content. An array of molecules, including initiation molecules of the complement system, are involved in marking dead cells for uptake. After binding of thes...

Descripción completa

Detalles Bibliográficos
Autores principales: Trouw, Leendert A., Nilsson, Sara C., Gonçalves, Isabel, Landberg, Göran, Blom, Anna M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212022/
https://www.ncbi.nlm.nih.gov/pubmed/15967823
http://dx.doi.org/10.1084/jem.20050189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212022/
https://www.ncbi.nlm.nih.gov/pubmed/15967823
http://dx.doi.org/10.1084/jem.20050189

Ejemplares similares