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C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation
After cell death, via apoptosis or necrosis, the uptake of dead cells by neighboring cells or phagocytes prevents the release of intracellular content. An array of molecules, including initiation molecules of the complement system, are involved in marking dead cells for uptake. After binding of thes...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212022/ https://www.ncbi.nlm.nih.gov/pubmed/15967823 http://dx.doi.org/10.1084/jem.20050189 |