Interleukin (IL)-4 inhibits IL-10 to promote IL-12 production by dendritic cells

Interleukin (IL)-4 is known to be the most potent cytokine that can initiate Th2 cell differentiation. Paradoxically, IL-4 instructs dendritic cells (DCs) to promote Th1 cell differentiation. We investigated the mechanisms by which IL-4 directs CD4 T cells toward the Th1 cell lineage. Our study demo...

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Detalles Bibliográficos
Autores principales: Yao, Yongxue, Li, Wei, Kaplan, Mark H., Chang, Cheong-Hee
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212025/
https://www.ncbi.nlm.nih.gov/pubmed/15967820
http://dx.doi.org/10.1084/jem.20050324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212025/
https://www.ncbi.nlm.nih.gov/pubmed/15967820
http://dx.doi.org/10.1084/jem.20050324

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