A Natural Immunological Adjuvant Enhances T Cell Clonal Expansion through a CD28-dependent, Interleukin (IL)-2–independent Mechanism

The adoptive transfer of naive CD4(+) T cell receptor (TCR) transgenic T cells was used to investigate the mechanisms by which the adjuvant lipopolysaccharide (LPS) enhance T cell clonal expansion in vivo. Subcutaneous administration of soluble antigen (Ag) resulted in rapid and transient accumulati...

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Detalles Bibliográficos
Autores principales: Khoruts, Alexander, Mondino, Anna, Pape, Kathryn A., Reiner, Steven L., Jenkins, Marc K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212094/
https://www.ncbi.nlm.nih.gov/pubmed/9432980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212094/
https://www.ncbi.nlm.nih.gov/pubmed/9432980

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