Promiscuous Presentation and Recognition of Nucleosomal Autoepitopes in Lupus: Role of Autoimmune T Cell Receptor α Chain

T cells specific for nucleosomal autoepitopes are selectively expanded in lupus mice and these Th cells drive autoimmune B cells to produce pathogenic antinuclear antibodies. We transfected the TCR-α and -β chain genes of a representative, pathogenic autoantibody-inducing Th clone specific for the n...

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Detalles Bibliográficos
Autores principales: Shi, Yan, Kaliyaperumal, Arunan, Lu, Liangjun, Southwood, Scott, Sette, Alessandro, Michaels, Marissa A., Datta, Syamal K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212116/
https://www.ncbi.nlm.nih.gov/pubmed/9449717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212116/
https://www.ncbi.nlm.nih.gov/pubmed/9449717

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