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Interleukin 7 Transgenic Mice Develop Chronic Colitis with Decreased Interleukin 7 Protein Accumulation in the Colonic Mucosa

We have demonstrated that intestinal epithelial cells produce interleukin 7 (IL-7), and IL-7 serves as a potent regulatory factor for proliferation of intestinal mucosal lymphocytes expressing functional IL-7 receptor. To clarify the mechanism by which locally produced IL-7 regulates the mucosal lym...

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Detalles Bibliográficos
Autores principales: Watanabe, Mamoru, Ueno, Yoshitaka, Yajima, Tomoharu, Okamoto, Susumu, Hayashi, Tatsuhiko, Yamazaki, Motomi, Iwao, Yasushi, Ishii, Hiromasa, Habu, Sonoko, Uehira, Masahiro, Nishimoto, Hirofumi, Ishikawa, Hiromichi, Hata, Jun-ichi, Hibi, Toshifumi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212121/
https://www.ncbi.nlm.nih.gov/pubmed/9449719