Infected Cell Protein (ICP)47 Enhances Herpes Simplex Virus Neurovirulence by Blocking the CD8(+) T Cell Response

The herpes simplex virus (HSV) infected cell protein (ICP)47 blocks CD8(+) T cell recognition of infected cells by inhibiting the transporter associated with antigen presentation (TAP). In vivo, HSV-1 replicates in two distinct tissues: in epithelial mucosa or epidermis, where the virus enters senso...

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Detalles Bibliográficos
Autores principales: Goldsmith, Kim, Chen, Wei, Johnson, David C., Hendricks, Robert L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212130/
https://www.ncbi.nlm.nih.gov/pubmed/9449714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212130/
https://www.ncbi.nlm.nih.gov/pubmed/9449714

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