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Infected Cell Protein (ICP)47 Enhances Herpes Simplex Virus Neurovirulence by Blocking the CD8(+) T Cell Response
The herpes simplex virus (HSV) infected cell protein (ICP)47 blocks CD8(+) T cell recognition of infected cells by inhibiting the transporter associated with antigen presentation (TAP). In vivo, HSV-1 replicates in two distinct tissues: in epithelial mucosa or epidermis, where the virus enters senso...
Autores principales: | Goldsmith, Kim, Chen, Wei, Johnson, David C., Hendricks, Robert L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212130/ https://www.ncbi.nlm.nih.gov/pubmed/9449714 |
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