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Inhibition of Apoptosis in Chlamydia-infected Cells: Blockade of Mitochondrial Cytochrome c Release and Caspase Activation

We report that chlamydiae, which are obligate intracellular bacterial pathogens, possess a novel antiapoptotic mechanism. Chlamydia-infected host cells are profoundly resistant to apoptosis induced by a wide spectrum of proapoptotic stimuli including the kinase inhibitor staurosporine, the DNA-damag...

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Detalles Bibliográficos
Autores principales: Fan, Tao, Lu, Hang, Hu, He, Shi, Lianfa, McClarty, Grant A., Nance, Dwight M., Greenberg, Arnold H., Zhong, Guangming
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212145/
https://www.ncbi.nlm.nih.gov/pubmed/9463399