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Inhibition of Apoptosis in Chlamydia-infected Cells: Blockade of Mitochondrial Cytochrome c Release and Caspase Activation
We report that chlamydiae, which are obligate intracellular bacterial pathogens, possess a novel antiapoptotic mechanism. Chlamydia-infected host cells are profoundly resistant to apoptosis induced by a wide spectrum of proapoptotic stimuli including the kinase inhibitor staurosporine, the DNA-damag...
Autores principales: | Fan, Tao, Lu, Hang, Hu, He, Shi, Lianfa, McClarty, Grant A., Nance, Dwight M., Greenberg, Arnold H., Zhong, Guangming |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212145/ https://www.ncbi.nlm.nih.gov/pubmed/9463399 |
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