Cargando…

Conformational Correction Mechanisms Aiding Antigen Recognition by a Humanized Antibody

The crystal structure of the complex between hen egg lysozyme and the Fv fragment of a humanized antilysozyme antibody was determined to 2.7-Å resolution. The structure of the antigen combining site in the complex is nearly identical to that of the complexed form of the parent mouse antibody, D1.3....

Descripción completa

Detalles Bibliográficos
Autores principales: Holmes, Margaret A., Buss, Timothy N., Foote, Jefferson
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212146/
https://www.ncbi.nlm.nih.gov/pubmed/9463398