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Conformational Correction Mechanisms Aiding Antigen Recognition by a Humanized Antibody

The crystal structure of the complex between hen egg lysozyme and the Fv fragment of a humanized antilysozyme antibody was determined to 2.7-Å resolution. The structure of the antigen combining site in the complex is nearly identical to that of the complexed form of the parent mouse antibody, D1.3....

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Detalles Bibliográficos
Autores principales: Holmes, Margaret A., Buss, Timothy N., Foote, Jefferson
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212146/
https://www.ncbi.nlm.nih.gov/pubmed/9463398

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