Wegener's Granulomatosis: Anti–proteinase 3 Antibodies Are Potent Inductors of Human Endothelial Cell Signaling and Leakage Response

Anti–neutrophil cytoplasmic antibodies (ANCAs) targeting proteinase 3 (PR3) have a high specifity for Wegener's granulomatosis (WG), and their role in activating leukocytes is well appreciated. In this study, we investigated the influence of PR3-ANCA and murine monoclonal antibodies on human um...

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Detalles Bibliográficos
Autores principales: Sibelius, Ulf, Hattar, Katja, Schenkel, Angelika, Noll, Thomas, Csernok, Elena, Gross, Wolfgang Ludwig, Mayet, Werner-Johannes, Piper, Hans-Michael, Seeger, Werner, Grimminger, Friedrich
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212153/
https://www.ncbi.nlm.nih.gov/pubmed/9463400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212153/
https://www.ncbi.nlm.nih.gov/pubmed/9463400

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