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Aerosol-induced Immunoglobulin (Ig)-E Unresponsiveness to Ovalbumin Does Not Require CD8(+) or T Cell Receptor (TCR)-γ/δ(+) T Cells or Interferon (IFN)-γ in a Murine Model of Allergen Sensitization

Mice exposed for 20 min daily to aerosolized ovalbumin (OVA) for 10 d at concentrations from 1 to 0.01% OVA made greatly reduced immunoglobulin (Ig)-E responses to subsequent immunogenic OVA challenges, given either intraperitoneally or by aerosol. This IgE-specific unresponsiveness lasted for at le...

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Detalles Bibliográficos
Autores principales: Seymour, Brian W.P., Gershwin, Laurel J., Coffman, Robert L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212168/
https://www.ncbi.nlm.nih.gov/pubmed/9480982