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Viral and Bacterial Infections Interfere with Peripheral Tolerance Induction and Activate CD8(+) T Cells to Cause Immunopathology

We studied the impact of various infectious and proinflammatory agents on the induction of peripheral T cell tolerance. Adoptive transfer of CD8(+) T cells from lymphocytic choriomeningitis virus (LCMV) T cell receptor transgenic mice into LCMV antigen transgenic mice expressing the LCMV glycoprotei...

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Detalles Bibliográficos
Autores principales: Ehl, Stephan, Hombach, Joachim, Aichele, Peter, Rülicke, Thomas, Odermatt, Bernhard, Hengartner, Hans, Zinkernagel, Rolf, Pircher, Hanspeter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212172/
https://www.ncbi.nlm.nih.gov/pubmed/9480986