Acidic Sphingomyelinase (ASM) Is Necessary for Fas-induced GD3 Ganglioside Accumulation and Efficient Apoptosis of Lymphoid Cells

Ceramides deriving from sphingomyelin hydrolysis are important mediators of apoptotic signals originating from Fas (APO-1/CD95). However, definitive evidence for the role played by individual sphingomyelinases is still lacking. We have analyzed lymphoblastoid cell lines derived from patients affecte...

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Detalles Bibliográficos
Autores principales: De Maria, Ruggero, Rippo, Maria Rita, Schuchman, Edward H., Testi, Roberto
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212183/
https://www.ncbi.nlm.nih.gov/pubmed/9500792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212183/
https://www.ncbi.nlm.nih.gov/pubmed/9500792

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