Tolerant B Lymphocytes Acquire Resistance to Fas-mediated Apoptosis after Treatment with Interleukin 4 but Not after Treatment with Specific Antigen Unless a Surface Immunoglobulin Threshold Is Exceeded

Susceptibility to Fas-mediated apoptosis in nontolerant B cells is regulated in a receptor-specific fashion. To explore the regulation of Fas killing in tolerant, autoreactive B cells, mice doubly transgenic for hen egg lysozyme (HEL)–specific B cell receptors and soluble HEL were examined. Engageme...

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Detalles Bibliográficos
Autores principales: Foote, Linda C., Marshak-Rothstein, Ann, Rothstein, Thomas L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212184/
https://www.ncbi.nlm.nih.gov/pubmed/9500787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212184/
https://www.ncbi.nlm.nih.gov/pubmed/9500787

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