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Human Immunodeficiency Virus Type 1 Vpr Is a Positive Regulator of  Viral Transcription and Infectivity in Primary Human Macrophages

It is currently well established that HIV-1 Vpr augments viral replication in primary human macrophages. In its virion-associated form, Vpr has been suggested to aid efficient translocation of the proviral DNA into the cell nucleus. Although Vpr growth-arrests dividing T cells, the relevance of this...

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Detalles Bibliográficos
Autores principales: Subbramanian, Ramu A., Kessous-Elbaz, Allegria, Lodge, Robert, Forget, Janique, Yao, Xiao-Jian, Bergeron, Dominique, Cohen, Eric A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212198/
https://www.ncbi.nlm.nih.gov/pubmed/9529326