α/β–T Cell Receptor (TCR)(+)CD4(−)CD8(−) (NKT) Thymocytes Prevent Insulin-dependent Diabetes Mellitus in Nonobese Diabetic (NOD)/Lt Mice by the Influence of Interleukin (IL)-4 and/or IL-10

We have previously shown that nonobese diabetic (NOD) mice are selectively deficient in α/β-T cell receptor (TCR)(+)CD4(−)CD8(−) NKT cells, a defect that may contribute to their susceptibility to the spontaneous development of insulin-dependent diabetes mellitus (IDDM). The role of NKT cells in prot...

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Detalles Bibliográficos
Autores principales: Hammond, Kirsten J.L., Poulton, Lynn D., Palmisano, Linda J., Silveira, Pablo A., Godfrey, Dale I., Baxter, Alan G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212199/
https://www.ncbi.nlm.nih.gov/pubmed/9529321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212199/
https://www.ncbi.nlm.nih.gov/pubmed/9529321

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