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α/β–T Cell Receptor (TCR)(+)CD4(−)CD8(−) (NKT) Thymocytes Prevent Insulin-dependent Diabetes Mellitus in Nonobese Diabetic (NOD)/Lt Mice by the Influence of Interleukin (IL)-4 and/or IL-10
We have previously shown that nonobese diabetic (NOD) mice are selectively deficient in α/β-T cell receptor (TCR)(+)CD4(−)CD8(−) NKT cells, a defect that may contribute to their susceptibility to the spontaneous development of insulin-dependent diabetes mellitus (IDDM). The role of NKT cells in prot...
Autores principales: | Hammond, Kirsten J.L., Poulton, Lynn D., Palmisano, Linda J., Silveira, Pablo A., Godfrey, Dale I., Baxter, Alan G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212199/ https://www.ncbi.nlm.nih.gov/pubmed/9529321 |
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