Transgene Expression of bcl-x(L) Permits Anti-immunoglobulin (Ig)–induced Proliferation in xid B Cells

Mutations in the tyrosine kinase, Btk, result in a mild immunodeficiency in mice (xid). While B lymphocytes from xid mice do not proliferate to anti-immunoglobulin (Ig), we show here induction of the complete complement of cell cycle regulatory molecules, though the level of induction is about half...

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Detalles Bibliográficos
Autores principales: Solvason, Nanette, Wu, Wei Wei, Kabra, Nisha, Lund-Johansen, Fridjtof, Roncarolo, Maria Grazia, Behrens, Timothy W., Grillot, Didier A.M., Nunez, Gabriel, Lees, Emma, Howard, Maureen
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212200/
https://www.ncbi.nlm.nih.gov/pubmed/9529324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212200/
https://www.ncbi.nlm.nih.gov/pubmed/9529324

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