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Ca(2+) Signaling Modulates Cytolytic T Lymphocyte Effector Functions

Cytolytic T cells use two mechanisms to kill virally infected cells, tumor cells, or other potentially autoreactive T cells in short-term in vitro assays. The perforin/granule exocytosis mechanism uses preformed cytolytic granules that are delivered to the target cell to induce apoptosis and eventua...

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Detalles Bibliográficos
Autores principales: Esser, Mark T., Haverstick, Doris M., Fuller, Claudette L., Gullo, Charles A., Braciale, Vivian Lam
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212215/
https://www.ncbi.nlm.nih.gov/pubmed/9529322