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HIV-1 Directly Kills CD4(+) T Cells by a Fas-independent Mechanism

The mechanism by which HIV-1 induces CD4(+) T cell death is not known. A fundamental issue is whether HIV-1 primarily induces direct killing of infected cells or indirectly causes death of uninfected bystander cells. This question was studied using a reporter virus system in which infected cells are...

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Detalles Bibliográficos
Autores principales: Gandhi, Rajesh T., Chen, Benjamin K., Straus, Stephen E., Dale, Janet K., Lenardo, Michael J., Baltimore, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212217/
https://www.ncbi.nlm.nih.gov/pubmed/9529327