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HIV-1 Directly Kills CD4(+) T Cells by a Fas-independent Mechanism
The mechanism by which HIV-1 induces CD4(+) T cell death is not known. A fundamental issue is whether HIV-1 primarily induces direct killing of infected cells or indirectly causes death of uninfected bystander cells. This question was studied using a reporter virus system in which infected cells are...
Autores principales: | Gandhi, Rajesh T., Chen, Benjamin K., Straus, Stephen E., Dale, Janet K., Lenardo, Michael J., Baltimore, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212217/ https://www.ncbi.nlm.nih.gov/pubmed/9529327 |
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