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B-1 Cell Development: Evidence for an Uncommitted Immunoglobulin (Ig)M(+) B Cell Precursor in B-1 Cell Differentiation
Murine phosphatidyl choline (PtC)–specific B cells in normal mice belong exclusively to the B-1 subset. Analysis of anti-PtC (V(H)12 and V(H)12/Vκ4) transgenic (Tg) mice indicates that exclusion from B-0 (also known as B-2) occurs after immunoglobulin gene rearrangement. This predicts that PtC-speci...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1998
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212222/ https://www.ncbi.nlm.nih.gov/pubmed/9547343 |