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B-1 Cell Development: Evidence for an Uncommitted Immunoglobulin (Ig)M(+) B Cell Precursor in B-1 Cell Differentiation

Murine phosphatidyl choline (PtC)–specific B cells in normal mice belong exclusively to the B-1 subset. Analysis of anti-PtC (V(H)12 and V(H)12/Vκ4) transgenic (Tg) mice indicates that exclusion from B-0 (also known as B-2) occurs after immunoglobulin gene rearrangement. This predicts that PtC-speci...

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Detalles Bibliográficos
Autores principales:	Clarke, Stephen H., Arnold, Larry W.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1998
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212222/ https://www.ncbi.nlm.nih.gov/pubmed/9547343

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