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Impaired Interleukin 4 Signaling in T Helper Type 1 Cells

Cluster of differentation (CD)4(+) T helper cells (Th)1s fail to produce interleukin (IL)-4. Even if restimulated in the presence of IL-4, a condition that induces IL-4–producing capacity in naive CD4(+) T cells, Th1s fail to become IL-4 producers. We report that Th1 cells have a major impairment in...

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Detalles Bibliográficos
Autores principales: Huang, Hua, Paul, William E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212231/
https://www.ncbi.nlm.nih.gov/pubmed/9547341