The Normal Counterpart of IgD Myeloma Cells in Germinal Center Displays Extensively Mutated IgVH Gene, Cμ–Cδ Switch, and λ Light Chain Expression

Human myeloma are incurable hematologic cancers of immunoglobulin-secreting plasma cells in bone marrow. Although malignant plasma cells can be almost eradicated from the patient's bone marrow by chemotherapy, drug-resistant myeloma precursor cells persist in an apparently cryptic compartment....

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Detalles Bibliográficos
Autores principales: Arpin, Christophe, de Bouteiller, Odette, Razanajaona, Diane, Fugier-Vivier, Isabelle, Brière, Francine, Banchereau, Jacques, Lebecque, Serge, Liu, Yong-Jun
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212232/
https://www.ncbi.nlm.nih.gov/pubmed/9547329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212232/
https://www.ncbi.nlm.nih.gov/pubmed/9547329

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