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Interleukin 4 Gene–defective Mice Reconstituted with Wild-type Bone Marrow Fail to Produce Normal Immunoglobulin E Levels
The ability to reconstitute interleukin (IL)-4(−/−) mice with bone marrow of IL-4(+/+) mice was investigated. The absence of the IL-4(−/−) gene in donor or recipient cells did not impair the reconstitution. All immunoglobulin (Ig) subsets occurred at normal serum levels except for IgE and to some ex...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1998
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212264/ https://www.ncbi.nlm.nih.gov/pubmed/9565640 |