Inhibition of Caspases Increases the Sensitivity of L929 Cells to Necrosis Mediated by Tumor Necrosis Factor

Murine L929 fibrosarcoma cells treated with tumor necrosis factor (TNF) rapidly die in a necrotic way, due to excessive formation of reactive oxygen intermediates. We investigated the role of caspases in the necrotic cell death pathway. When the cytokine response modifier A (CrmA), a serpin-like cas...

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Detalles Bibliográficos
Autores principales: Vercammen, Dominique, Beyaert, Rudi, Denecker, Geertrui, Goossens, Vera, Van Loo, Geert, Declercq, Wim, Grooten, Johan, Fiers, Walter, Vandenabeele, Peter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212268/
https://www.ncbi.nlm.nih.gov/pubmed/9565639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212268/
https://www.ncbi.nlm.nih.gov/pubmed/9565639

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