The Phosphotyrosine Phosphatase SHP-2 Participates in a Multimeric Signaling Complex and Regulates T Cell Receptor (TCR) coupling to the Ras/Mitogen-activated Protein Kinase (MAPK) Pathway in Jurkat T Cells

Src homology 2 (SH2) domain–containing phosphotyrosine phosphatases (SHPs) are increasingly being shown to play critical roles in protein tyrosine kinase–mediated signaling pathways. The role of SHP-1 as a negative regulator of T cell receptor (TCR) signaling has been established. To further explore...

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Detalles Bibliográficos
Autores principales: Frearson, Julie A., Alexander, Denis R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212277/
https://www.ncbi.nlm.nih.gov/pubmed/9565634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212277/
https://www.ncbi.nlm.nih.gov/pubmed/9565634

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