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Disruption of Lymphocyte Function and Signaling in CD45–associated Protein–null Mice

CD45-AP specifically associates with CD45, a protein tyrosine phosphatase essential for lymphocyte differentiation and antigen receptor–mediated signal transduction. CD45 is thought to mediate antigen receptor signaling by dephosphorylating regulatory tyrosine residues on Src family protein tyrosine...

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Detalles Bibliográficos
Autores principales: Matsuda, Akio, Motoya, Satoshi, Kimura, Shioko, McInnis, Renee, Maizel, Abby L., Takeda, Akiko
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212302/
https://www.ncbi.nlm.nih.gov/pubmed/9607926