Nf1 Regulates Hematopoietic Progenitor Cell Growth and Ras Signaling in Response to Multiple Cytokines

Neurofibromin, the protein encoded by the NF1 tumor-suppressor gene, negatively regulates the output of p21(ras) (Ras) proteins by accelerating the hydrolysis of active Ras-guanosine triphosphate to inactive Ras-guanosine diphosphate. Children with neurofibromatosis type 1 (NF1) are predisposed to j...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, You-Yan, Vik, Terry A., Ryder, John W., Srour, Edward F., Jacks, Tyler, Shannon, Kevin, Wade Clapp, D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212307/
https://www.ncbi.nlm.nih.gov/pubmed/9607929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212307/
https://www.ncbi.nlm.nih.gov/pubmed/9607929

Ejemplares similares