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Nf1 Regulates Hematopoietic Progenitor Cell Growth and Ras Signaling in Response to Multiple Cytokines

Neurofibromin, the protein encoded by the NF1 tumor-suppressor gene, negatively regulates the output of p21(ras) (Ras) proteins by accelerating the hydrolysis of active Ras-guanosine triphosphate to inactive Ras-guanosine diphosphate. Children with neurofibromatosis type 1 (NF1) are predisposed to j...

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Detalles Bibliográficos
Autores principales:	Zhang, You-Yan, Vik, Terry A., Ryder, John W., Srour, Edward F., Jacks, Tyler, Shannon, Kevin, Wade Clapp, D.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1998
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212307/ https://www.ncbi.nlm.nih.gov/pubmed/9607929

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